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diagnosis differential rheumatology algorithm dermatology eosinophilia eosinophils hes systemic treatment allergy cerebritis classification cns common cryofibrinogenemia cryoglobulinemia cryoglobulins cvid eoe
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Secondary Hypereosinophilic ... suspect underlying hematologic ... disorders • Diagnosis ... #Hematology #eosinophilia ... eosinophils #diagnosis #management
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... • Screen for secondary ... causes of eosinophilia ... (common causes ... Differential #diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia ... Syndrome (HES) ... blood eosinophilia Secondary ... Causes: - Allergic ... eosinophilia #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
leakage of RBC's secondary ... Thrombocytopenia: ITP • Secondary ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Differential Diagnosis Secondary ... Chronic inflammatory disorders ... Myelodysplastic syndrome ... #hematology #secondary
Secondary Causes of Esophageal Eosinophilia (EoE) - Differential Diagnosis • Gastroesophageal reflux disease • Eosinophilic gastrointestinal
Secondary Causes ... Achalasia • Hypereosinophilic ... Connective tissue disorders ... • Autoimmune disorders ... #Causes #gastroenterology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... , Seizure disorders ... autoantibodies that will cause ... APS), Secondary ... cerebritis #diagnosis #management
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... • Nephrotic syndrome ... NailDisorders #Systemic #Secondary ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... hematological disorders ... Type III Often Secondary ... classification #rheumatology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... drug reactions - Secondary ... therapies-common - Secondary ... #hematology
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