39 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... PT, aPTT(liver disease ... pylori test (GI symptoms ... #Differential #Diagnosis ... #hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and clinical associations ... and duration of symptoms ... angioedema Other symptoms ... #rheumatology #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... Viral Infection Clinical ... Monoclonal IgM Includes Disorders ... hemolytic #anemia #hematology
Restrictive Cardiomyopathy - Diagnosis and Causes
Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema)
Physical
Cardiomyopathy - Diagnosis ... and Causes Clinical ... ↑ "Right Sided-Symptoms ... Sarcomeric Protein Disorders ... #Causes #differential
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
as jaundice on clinical ... examination; nonspecific symptoms ... and stress may cause ... bilirubin #hepatology #diagnosis ... #gastroenterology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Is visual loss caused ... acute ischemic disorder ... Clinical manifestations ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... , Seizure disorders ... Cerebrovascular Disease ... autoantibodies that will cause ... CNS #neurology #rheumatology
Dysphagia - Differential Diagnosis Framework

Symptom | Diagnosis
• Solid-food dysphagia present for months to years | Mechanical
Framework Symptom ... | Diagnosis • ... stroke, Parkinson disease ... the underlying cause ... #Management #gastroenterology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... Lymphoproliferative Disorders ... ANA #patterns #rheumatology ... #diagnosis #differential
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... cryoglobulinemia Associated Disorders ... : • + Clinical ... cryoglobulins • Negative causes ... #rheumatology #