17 results
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Disorders of Pigmentations ... - Differential Diagnosis ... of hair, eyes, skin ... McCune Albright syndrome ... #disorders #skin
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Diagnosis: • ... lymphoproliferative disorders ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Skin Hyperpigmentation - Differential Diagnosis Algorithm
Diffuse:
 • Tanning
 • Adverse cutaneous drug eruption
 • Addison's disease
Skin Hyperpigmentation ... - Differential Diagnosis ... McCune Albright syndrome ... #disorders #skin ... #dermatology #Differential
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... hypertrichosis, hyperpigmentation ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... general feeling of ill ... , breast CA - Hematologic ... #diagnosis #dermatology ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... just beneath the skin ... #diagnosis #hematology ... #oncology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
neuritis - Giant cell ... Hemochromatosis • Hyperpigmentation ... Scleroderma Thickened skin ... #differential #diagnosis ... #rheumatology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
MYH9-Related Disorder ... structure and cell ... Defects #comparison #table ... #differential #diagnosis ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Seizures • Strokes Skin ... Erythematosus #Diagnosis