12 results
hematology differential causes management oncology erythematosus sle systemic activation algorithm aplastic cerebritis cns extravascular hemolysis hemolytic intravascular korsakoff macrophage mas
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
- Differential Diagnosis ... • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Diseases: • Systemic lupus ... #Hematology
Korsakoff Syndrome Clinical Findings: • Confabulation: Usually initial phase of the disease • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... • Anterograde amnesia ... presentation of Thiamine deficiency ... Encephalopathy Treatment ... #neurology #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... permeability Diagnosis ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... usually IgG) (e.g. lupus ... G6PD deficiency) ... #hematology #anemia
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
Nutritional: DiabetesB12 deficiency ... Vasculitis, Sjogren's, Lupus ... Paraprotein-associated (POEMS syndrome ... #differential #diagnosis ... #causes #neurology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Acute hemolysis, deficiency ... anemia, Rebound ... effect from treatment ... Kawasaki, Nephrotic syndrome
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... Treatment: ... #oncology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SJIA], systemic lupus ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... disease • Prolidase deficiency ... lymphopenia, low PLT • Anemia ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
or folic acid deficiency ... factor (GCSF) treatments ... • Copper deficiency ... marrow studies Treatment ... #diagnosis #hematology
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