256 results
Trichodysplasia spinulosa: follicles plugged w/ hyperkeratotic & parakeratotic debris, excessive inner root sheath differentiation towards keratinization.
EM shows intranuclear ... icosahedral polyomavirus inclusions ... spinulosa #Pathology #Microscopy
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
treat hypertension caused ... spironolactone body inclusions ... spironolactone had inclusions ... intracytoplasmic inclusions ... Clinical #Gross #Microscopy
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... cells on urine microscopy ... ) • Anti-GBM ... with polyangiitis/microscopic ... Diagnosis #Algorithm #Causes
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine sediment Microscopic ... urine sediment by microscopy ... pain + gross or microscopic ... disease Renal Causes ... microscopic and
Causes of Erythema Nodosum - Mnemonic

NO cause found in 60% of cases
Drugs (antibiotics e.g., sulfonamides, amoxicillin)
Oral
Causes of Erythema ... Mnemonic NO cause ... found in 60% of cases ... Viral: HSV, EBV ... Nodosum #Mnemonic #Causes
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
NEJMoa1313731 CONCLUSIONS ... cardiovascular causes ... dCHF #Cardiology #EBM
Pity this Giant Pronormoblast from an elderly pt w pure red cell aplasia. In the proper
enlarged w viral inclusions ... Pathology #Smear #Microscopy
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Syndrome (ASS), Inclusion ... Body Myositis (IBM
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Infectious: Influenza, EBV ... dermato-, poly-, inclusion ... Differential #Diagnosis #causes
Glomerulonephritis - Differential Diagnosis Framework
ANCA:
 • C-ANCA: GPA (Wegener's)
 • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Wegener's) • P-ANCA: Microscopic ... Strauss) Anti-GBM ... diagnosis #nephrology #causes