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causes hepatology classification lfts transaminitis chemistry ddxof drug druginduced dyspnea elevated elevation em endocrinology euvolemic function gastroenterology gout hepatitis high
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... presentation • Chronic ... #differential # ... gastroenterology #algorithm
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis ... Algorithm DILI ... dechallenge • Acute ... #Injury #Diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Diagnosis Framework ... Cirrhosis • Chronic ... Hepatopathy • Acute ... (>1000): • DILI ... injury) • Ischemic
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... > 3 • Chronic ... diagnosis #algorithm
Non-ACS Myocardial Injury - Elevated Troponin Differential Diagnosis and Workup Algorithm • Chronic Myocardial Injury: End
Algorithm • ... Chronic Myocardial ... Shock, Hypoxemia, Anemia ... Metabolic (ie acidosis ... #Diagnosis #Algorithm
Renal Tubular Acidosis - Differential Diagnosis Algorithm Decreased Serum K, Urine pH < 5.5 - Proximal RTA Decreased
Diagnosis Algorithm ... Tubulointerstitial injury ... tract obstruction, Chronic ... Jain via UNC IM ... Diagnosis #Algorithm
Differential Diagnosis and Evaluation of Hyponatremia: 1) Identification of onset (acute vs. chronic) 2) Presence of symptoms (HA,
Differential Diagnosis ... vs. chronic) 2) ... history (cardiac, liver ... #EM #IM #Nephro ... #Algorithm #Ddxof
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
> 2 • NASH, Chronic ... > 3 • Chronic ... Unconjugated Bili ... #chemistry #diagnosis ... #differential #
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Hyperuricemia - Differential ... Diagnosis Algorithm ... - Hemolytic Anemia ... • Diabetic acidosis ... #Diagnosis #Algorithm
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
of Seizures - Differential ... Diagnosis Algorithm ... Traumatic brain injury ... , Liver failure, ... #Diagnosis #Algorithm
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