11 results
Shotgun Laboratory Testing for Severe Acute Livery Injury

https://www.journalofhospitalmedicine.com/jhospmed/article/143598/hospital-medicine/ammonia-levels-and-hepatic-encephalopathy-patients-known

#TWDFNR #Testing #Laboratory #LiverInjury #Diagnosis #Workup #Hepatology #EBM #ChoosingWisely
Shotgun Laboratory ... Testing for Severe ... Acute Livery Injury ... #Diagnosis #Workup ... #Hepatology #EBM
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Differential Diagnosis ... Hepatopathy • Acute ... injury) • Ischemic ... #hepatology #transaminitis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... > 20x normal - Acute ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #diagnosis
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... hepatocellular injury ... #Laboratory #Values ... Interpretation #diagnosis ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... dechallenge • Acute ... hepatitis #DILI #DrugInduced ... #Liver #Injury ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... injury < 26 weeks ... #chemistry #diagnosis ... #differential #Hepatology ... transaminitis #LFTs
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... —100-fold with acute ... LiverFailure #Hepatic #Hepatology ... #Laboratory #Diagnosis ... #Testing
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... liver failure ... injury, though ... Necrosis) If mild laboratory ... #Management #Hepatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Screening Tests for Acute ... profile, including liver ... function tests (LFTs ... (to support a diagnosis ... #workup #diagnosis
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... - Acute Hemolytic ... Lung Injury (TRALI ... eruptions, diarrhea, liver ... #Transfusions #diagnosis