13 results
Shotgun Laboratory Testing for Severe Acute Livery Injury

https://www.journalofhospitalmedicine.com/jhospmed/article/143598/hospital-medicine/ammonia-levels-and-hepatic-encephalopathy-patients-known

#TWDFNR #Testing #Laboratory #LiverInjury #Diagnosis #Workup #Hepatology #EBM #ChoosingWisely
Shotgun Laboratory ... Testing for Severe Acute ... Livery Injury ... #LiverInjury #Diagnosis ... #Workup #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... dechallenge • Acute ... hepatitis #DILI #DrugInduced ... #Liver #Injury ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Injury (DILI) ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Liver Injury: ... intestines, white blood ... #algorithm #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
brain, heart, blood ... hepatocellular injury ... #Tests #LFTs #Laboratory ... Interpretation #diagnosis ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Mixed - Check Acute ... injury < 26 weeks ... intestines, White blood ... #chemistry #diagnosis ... #differential #Hepatology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... —100-fold with acute ... chronic anemia; blood ... LiverFailure #Hepatic #Hepatology ... #Laboratory #Diagnosis
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... liver failure ... injury, though ... Necrosis) If mild laboratory ... #Management #Hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... RBCs, muscle, liver ... deficiency of red blood ... : • Early acute ... #Laboratory
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... ABO incompatible blood ... DIC • Severe Liver ... #Coagulation #diagnosis ... causes #treatment #management