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diagnosis differential transaminitis algorithm chemistry dili drug enzymes functiontest hepatocellular idiosyncratic induced interpretation management rvalue
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... • AST/ALT elevation ... Liver Injury? ... #differential #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
(LFTs) Elevation ... Hepatocellular injury ... injury Sinai ... #FunctionTest #LFTs ... #diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... Mixed DILI • Cholestatic ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Bilirubin - +/- elevation ... Enzyme Elevation ... #differential #Hepatology ... transaminitis #LFTs
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