16 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Hemolysis, Elevated Liver ... child * Severe cases ... exchange 2) Fatty liver ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
) • Advanced Liver ... (VIII is most common ... Summary #table #comparison ... #diagnosis #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... deficiency in the common ... inhibitors to the common ... • Reduced liver ... #hematology #coagulation
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • Liver ... and M panel Management ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... inhibitors to the common ... Reduced liver synthesis ... #diagnosis #differential ... #hematology #coagulation
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
and Management ... the setting of liver ... lung disease Caused ... • Dyspnea - Common ... #hepatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
symptoms can mimic common ... Diagnosis via genetic ... lymph node, or liver ... #management #treatment ... #hematology
Cutaneous larva migrans skin Rash
25 F recent Caribbean vacation, walked barefoot on sand and now with
with creepy rash. diagnosis ... Adult hookworms live ... larva #migrans #skinRash ... #dermatology #clinical ... #photo
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology