11 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hematologic: Acute blood ... loss, Acute hemolysis ... Inflammatory Conditions: Rheumatologic ... #Algorithm #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... Immunoglobulin M (IgM) • Blood ... sensitize red blood ... chills, flank pain ... #anemia #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
(e.g. cancer, infection ... Microangiopathic hemolytic ... G6PD deficiency), Infections ... Production #Index #hematology ... #differential #diagnosis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Internal (RBC) - Infections ... - Peripheral Blood ... #hematology
Janeway Lesions in Endocarditis seen on Physical Exam 

Dr Supradip Ghosh
@dr_supradip

36 year old male with history
Blood cultures growing ... His sister shared ... Infective Endocarditis ... could have been diagnosed ... #dermatology #soles
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
: Fever, flank pain ... exposure can be faster ... Infection - Infection ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
: Fever, flank pain ... exposure can be faster ... • Infection - ... #Transfusions #diagnosis ... #management #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
burning sensation or pain ... Differential Diagnosis ... vasculitis (inflamed blood ... #rash #diagnosis ... #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... , bleeding, infections ... bruising, bleeding, infection ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... nodosum • Immune hemolytic ... anemia • Pain ... Workup: • Full Blood ... classification #hematology