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Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
deficiency or inhibitor ... deficiency or inhibitor ... deficiency or inhibitor ... Thromboplastin #laboratory #hematology
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
deficiency, or an inhibitor ... Patient has a factor inhibitor ... Study #diagnosis #hematology ... pathophysiology #hematology
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Direct Thrombin Inhibitor ... prolonged #diagnosis #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(Bruton kinase inhibitor ... Venetoclax (BCL2 inhibitor ... Leukemia #oncology #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
diagnosis #models #hematology ... Dabigatran #thrombin #inhibitor
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Deficiency or an inhibitor ... - factor VIII inhibitor ... )* • Acquired inhibitor ... )* • Acquired inhibitor ... Differential #Diagnosis #Hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
: Non specific inhibitor ... #differential #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
tests to detect an inhibitor ... Diagnosis #Workup #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Nonspecific inhibitor ... #differential #hematology
Medications to Avoid in Patients with G6PD Deficiency Due to Risk of Hemolysis - Chloroquine (Aralen)*
DS; Septra)* - Inhibitor ... #Pharmacology #Hematology
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