2425 results
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... direct thrombin inhibitors ... Inhibitors: Non ... specific inhibitor ... Causes #diagnosis #differential
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... Angiotensin-converting enzyme (ACE) inhibitors ... • Calcineurin Inhibitors ... #hyperkalemia #differential
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Direct Xa inhibitors ... Specific inhibitors ... Specific inhibitors ... Inhibitors ... Causes #diagnosis #differential
TNF-alpha Inhibitors

Dr. Ann Marie Kumfer @AnnKumfer

#TNFalpha #Inhibitors #Diagnosis #Differential #Indications
TNF-alpha Inhibitors ... #TNFalpha #Inhibitors ... #Diagnosis #Differential
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Extrarenal Proton pump inhibitor ... Tyrosine kinase inhibitors ... - Calcineurin inhibitors ... #Medications #differential
Infections in Patients on TNF-alpha Inhibitors - Differential Diagnosis
 • Viral: VZV, Hep B, Hep C,
Patients on TNF-alpha Inhibitors ... - Differential ... #TNFalpha #Inhibitors ... #Infections #Differential
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... Deficiency or an inhibitor ... - factor VIII inhibitor ... )* • Acquired inhibitor ... Bruising #Hemostasis #Differential
Cancer agents and Electrolyte Disorders
 • Hypocalcemia: Cisplatin from Low Mg, Cetuximab- due to low Mg
Axitinib,
Secondary Pth, BRAF inhibitors ... resistance, PD-1 Inhibitors ... mechanism, CTLA-4 inhibitors ... to low Mg, BRAF inhibitors ... chemotherapy #diagnosis #differential
Polyuria - Differential Diagnosis
Solute Diuresis
 • Na intake/saline
 • Glucosuria: Hyperglycemia, SGLT-2 inhibitors
 • Urea: Exogenous
Polyuria - Differential ... Hyperglycemia, SGLT-2 inhibitors ... #Polyuria #Differential
Metabolic Acidosis with Anion Gap - KILU Mnemonic

K - Ketoacidosis
	• DKA
		- With normal glucose, ask if
ask if on SGLT2 inhibitor ... ketoacidosis in SGLT2 inhibitors ... Acidosis #diagnosis #differential