279 results
management signs symptoms differential causes treatment syndrome pharmacology neurology hematology msk psychiatry nephrology rheumatology algorithm medications classification dermatology ophthalmology table
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... immune deficiency, Drugs ... Anti-IFN-y and JAK inhibitors
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
Pathogenesis and Clinical ... Group A Strep - Drugs ... necrosis factor a inhibitors ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Direct renin inhibitor ... • Calcineurin Inhibitors ... #differential #diagnosis ... #pathophysiology
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... necrosis factor-α inhibitors ... • Injection drug ... characteristic features Clinical ... Tuberculosis Diagnosis
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... Antimicrobials Drug-induced ... Tyrosine kinase inhibitors ... panitumumab) #Drugs ... #differential #diagnosis
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Drugs: Direct or ... drugs (e.g. direct ... Inhibitors: Non ... Prolonged #Causes #diagnosis
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Drugs a. ... Direct Xa inhibitors ... Drugs a. ... drugs e.g. direct ... Prolonged #Causes #diagnosis
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... necrosis factor-α inhibitors ... • Injection drug ... characteristic features Clinical ... Tuberculosis Diagnosis
Immune Reactions and Immunosuppressant Drugs Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2 Muromonab-CD3 - Monoclonal antibody Calcineurin
Immunosuppressant Drugs ... antibody Calcineurin inhibitors ... Immunosuppressant #Drugs ... #Pharmacology #Pathophysiology
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Aldosterone Release: ACE inhibitors ... #Hyperkalemia #Pathophysiology
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