53 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Direct Thrombin Inhibitor ... Prolonging the PT or APTT ... cause of Prolonged APTT ... ISNeducation #Abnormal #APTT ... prolonged #diagnosis #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Prolonged PT and aPTT ... the PT and the aPTT ... Causes #diagnosis #differential ... #hematology #coagulation
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm

aPTT: Intrinsic / Final
PT: Extrinsic / Final

By
Approach to Elevated aPTT ... / PT - Differential ... #Elevated #aPTT ... INR #Algorithm #Hematology ... #differential #
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... typically prolong aPTT ... may prolong the aPTT ... Causes #diagnosis #differential ... #hematology #coagulation
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
deficiency, or an inhibitor ... deficiencies and inhibitors ... PT and/or aPTT) ... Study #diagnosis #hematology ... pathophysiology #hematology
Lupus Nephritis Classification Algorithm

#Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis Classification ... Lupus #Nephritis #Classification ... Algorithm #diagnosis #differential ... #types #rheumatology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Thromboplastin Time (PTT ... deficiency or inhibitor ... deficiency or inhibitor ... deficiency or inhibitor ... Thromboplastin #laboratory #hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
INR), Prolonged PTT ... INR), Prolonged PTT ... (INR), Normal PTT ... #PPT #PT #INR #Differential ... Algorithm #Causes #Hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... antiglobulin test, PT/aPTT ... hemosiderin • PT/aPTT ... Microangiopathy #TMA #Differential ... Management #Algorithm #hematology
Break down Vasculitis based on vessel size
#Diagnosis #Rheumatology #Differential #Vasculitis #VesselSize #Small #Medium #Large #Classification
size #Diagnosis #Rheumatology ... #Differential # ... Medium #Large #Classification