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hepatology diagnosis chronic hepatitisb syndrome aclf alcoholic differential dili druginduced failure gastroenterology hepatorenal hepbv hrs indications kidney nephrology rheumatology sjogrens
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... severe liver injury ... liver failure ... #HBV #Treatment ... #Indications #management
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Algorithm • ... viremia or have cirrhosis ... HAV immunity; Liver ... #HBV #Algorithm ... #Treatment #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Brain Failure Lung ... Injury (DILI) ... Viral Hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... , HBV, HCV, HEV, ... dechallenge • Acute ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... , HBV, HCV, HEV, ... CA, small cell lung ... : < 1 • Cirrhosis ... #injury #hepatitis
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... (AKI) - Management ... Treat underlying liver ... #Injury #treatment ... #management
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... : - Acute kidney ... injury with serum ... #Management #Algorithm
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
disease: cirrhosis ... severe alcoholic hepatitis ... , or acute liver ... Normal kidney ultrasound ... Treatment Overview
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
vasculitis: 10%-16% Liver ... • Autoimmune hepatitis ... primary biliary cirrhosis ... phenomenon (16%) MSK ... MALT Lymphoma • Lung
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