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diagnosis management hepatology algorithm differential clinical aki blood cardiology causes cirrhosis failure hematology hepatitis indications infectiousdiseases lactate orthopedics pocus product
Clinical manifestations of acute liver failure Brain: Hepatic encephalopathy, Cerebral edema, Intracranial hypertension,
liver failure ... abnormalities Liver ... Subclinical myocardial injury ... pancreatitis Lungs ... : Acute lung injury
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Brain Failure Lung ... Injury (DILI) ... EmoryGastroHep #ACLF #Acute
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Liver Injury: ... Liver Injury: ... CA, small cell lung ... Liver Injury:
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... involvement, Kidney injury ... non-essential drug/HDS treatments ... dechallenge • Acute ... #Injury #Diagnosis
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
paracentesis (>5 liter ... ) - 8g per liter ... ascites removed • Acute ... kidney injury ( ... Management #Cirrhosis #treatment
Outpatient Hypertension Management Algorithm Monotherapy: • Thiazide/thiazide-like • ACE-I (non-black patients), • ARB
ARB • CCB (long ... Hemorrhage • Acute ... Syndrome • Acute ... Kidney Injury ... Amy Chung, MD, MSc
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
immunosuppression • Acute ... infection with severe liver ... injury (INR > 2 ... > 3 mg/dL) or acute ... liver failure
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... Treat underlying liver ... → No specific treatment ... straight cath or long-term ... #Kidney #Injury
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
Guide to Acute Kidney ... Injury (AKI) ... What to ask/look ... - TTE/liver fxn?
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
RBCs, muscle, liver ... Prosthetic valves Lung ... Pneumonia • Other lung ... : • Early acute ... hepatitis • Acute
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