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diagnosis algorithm indications lfts transaminitis acidosis aclf acute albumin causes chemistry chronic criticalcare elevation encephalopathy failure foamed gastroenterology grading hbv
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... Failure Infections Alcohol-Associated ... Injury (DILI) ... #Hepatology #gastroenterology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... cirrhosis, Portal ... #Injury #hepatology ... transaminitis #differential
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
for Albumin for Management ... of Cirrhosis ... • Acute kidney injury ... #Cirrhosis #treatment ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... ALT Ratios: • Alcoholic ... hepatitis: < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
injury < 26 weeks ... ALT Ratios: • Alcoholic ... hepatitis: < 1 • Cirrhosis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
or fibrosis • Cirrhosis ... injury (INR > 2 ... mg/dL) or acute liver ... #Indications #management ... #hepatology
Hepatic Encephalopathy - Diagnosis and Management Summary Definition: • Alteration in brain function manifested by neuropsychiatric symptoms
• Caused by liver ... Prevalence: At cirrhosis ... Constipation, Alcohol ... Encephalopathy #Grading #Classification ... #treatment #hepatology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
disease: cirrhosis ... , severe alcoholic ... Classification: ... Treatment Overview ... Hepatorenal #Syndrome #Hepatology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... stores in the liver ... beta-oxidation in the liver ... #diagnosis #differential ... #algorithm #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... or renal injury ... Hypoglycemia - Alcohol ... Injury: • Reduced ... #typea #typeb #classification
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