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diagnosis differential erythematosus hyperkalemia potassium systemic vasculitis acidosis blood cryoglobulinemia cryoglobulins elevation hcq hematology high hydroxychloroquine k lactate lactic levels
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Initial screening test ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology ... #management
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... if < 200ng/mL Best ... #rheumatology # ... pharmacology #levels #lupus ... #management
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
causing endothelial injury ... • They can cause ... (e.g. systemic lupus ... #classification ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... Non-autoimmune rheumatologic ... Kikuchi disease • Type-I ... • Malar rash - spares
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
again we might see ... liver or renal injury ... or diagnostic tests ... gluconeogenesis Liver Injury ... classification
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... neuromuscular injury ... diseases: syßtemic lupus ... High #Potassium #Classification ... #Causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... retinopathy Lab Tests ... vasculitis, and SLE ... differential #diagnosis #rheumatology ... #classification
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, rhabdo/crush injury ... Aldosterone, RTA Type ... Cortisol+ACTH stim test ... only if no clear cause ... and Elimination (see
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Pager Summary Type ... indirect Coombs test ... Related Acute Lung Injury ... Transfusions #diagnosis #management ... #hematology #reactions
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
such as: • SLE ... Diagnosis: • Clinical tests ... Antibodies to type ... Polychondritis #rheumatology ... #diagnosis #management
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