28 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Liver Injury (DILI ... Chronic - ongoing ↑ LFTs ... #differential # ... Diagnosis #Management
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... Liver Injury ... #differential # ... hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Differential Diagnosis ... 1000): • DILI (Drug-induced ... liver injury) ... Diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... : Liver Injury ... Injury Differential ... #Injury #Differential ... #Diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Diagnosis Algorithm ... • Others #LFTs ... Diagnosis #Algorithm ... #Causes
Jaundice Evaluation Algorithm #Diagnosis #Management #EM #IM #GI #Jaundice #Hyperbilirubinemia #Workup #Evaluation #Differential #Algorithm #Direct #Indirect
#Diagnosis #Management ... #EM #IM #GI #Jaundice ... Hyperbilirubinemia #Workup ... #Evaluation #Differential ... #Algorithm #Direct
Differential Diagnosis of Hypoglycemia
Evaluation of Hypoglycemia
Patients with known diabetes who are not systemically ill and can
Differential Diagnosis ... consider: - BMP - LFT ... #EM #IM #Hypoglycemia ... #Differential # ... Algorithm #Drugs
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Acute Liver Injury ... obstruction - Drug-Induced ... liver injury ... #Differential # ... Hepatology #Diagnosis
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypothyroid • Liver ... • Alcohol • Drugs ... Macrocytic #Anemia #differential ... #diagnosis #algorithm ... #hematology #workup
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Differential Diagnosis ... history (cardiac, liver ... renal disease), drug ... #EM #IM #Nephro ... #Algorithm #Ddxof