9 results
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... gammopathy of renal ... cyclophosphamide) #Acute ... #AKI #Cancer #Oncology ... #Differential #
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... Acute or chronic ... Compensation, Acute ... (short bowel syndrome ... bloodgas #Acid #Base
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
K+: • Tissue injury ... • Tumor lysis syndrome ... • Metabolic acidosis ... glycosides • High ... acute iatrogenic
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency - Differential ... intake: - Diets high ... Diuretic use - Renal ... seen • Lactic acidosis ... Manifestations #Differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... declines > ALT) • AKI ... + myoglobin AKI ... Isotonic fluid/Lactated
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential ... injury in the production ... cardiac output - Acute ... - Compartment syndrome ... peritonitis - Acute
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... • Present in high ... : • Early acute ... hepatitis • Acute
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Attempt if high ... initiation • Differential ... Renal Failure ... APML #diagnosis #management ... #hematology #oncology
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Acidosis B. ... injury F. ... antiphospholipid syndrome ... #Hyperkalemia #Differential ... #Diagnosis #High