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Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... , Compartment syndrome ... , Heat stroke, Metabolic ... Dermatomyositis) AKI
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
K+: • Tissue injury ... • Tumor lysis syndrome ... • Metabolic acidosis ... glycosides • High ... Elimination: • AKI
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Heat stroke - Metabolic ... declines > ALT) • AKI ... + myoglobin AKI
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Trauma/Crush injury ... - Tumor lysis syndrome ... infusions) - Metabolic ... acidosis - Hyperkalemia ... Excretion: •
Distal Renal Tubular Acidosis
Distal RTA is the true Nephrogenic RTA and can be truly divided into
Distal Renal Tubular ... Acidosis Distal ... diseases(Sjogren's Syndrome ... distal RTA - A high ... RTA #diagnosis #differential
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Trauma/Crush injury ... - Tumor lysis syndrome ... infusions) - Metabolic ... acidosis - Hyperkalemia ... Excretion: •
Causes of Hyperkalemia - Differential Diagnosis Framework
 • Cellular Shift:
   - Exercise
Exercise - Metabolic ... Acidosis - ... Decreased Urinary Excretion ... depletion, - AKI ... Causes #potassium #high
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Excretion Carbonic ... resistance • Metabolic ... irrigation • Management ... Loop Diuretics; High-Ceiling ... #Medications #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, rhabdo/crush injury ... K+ Excretion: ... , RTA Type IV, AI ... excretion ... Elimination (see Table
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential ... impairment of cellular metabolism ... from the blood by excretion ... sweat) - its metabolism ... - Compartment syndrome