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hepatology differential gastroenterology hepatitis treatment aclf aflp alcoholic chagas cirrhosis disease distention diuresis diuretics drug druginduced excretion failure fatty idiosyncratic
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... presentation • Chronic ... #differential #Diagnosis ... #algorithm #gastroenterology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Algorithm DILI ... for alternative causes ... dechallenge • Acute ... #Injury #Diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... Causes of Acute ... > 3 • Chronic
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Injury (DILI) ... #Chronic #Liver ... gastroenterology #management ... #diagnosis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... = nonspecific (nausea ... , vomiting, abdominal ... headache, malaise) → Acute ... 10x ULN), ↑Tbili/Dbili
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome • Diagnosis ... irrigation • Management ... Torsemide) • Acute ... Kidney stones caused ... Postoperative abdominal
Chronic Pancreatitis Definition: A pathologic fibroinflammatory syndrome of the pancreas in individuals with genetic, environmental, and/or other
Chronic Pancreatitis ... to parenchymal injury ... stress. 60% of CP cases ... Manifestations: • Abdominal ... #management #gastroenterology
Abdominal Distention - Differential Diagnostic Algorithm Ascites Bowel Dilatation Other Causes Mechanical Obstruction • Adhesions 60% • Volvulus 3% •
Abdominal Distention ... Dilatation Other Causes ... Pseudo-obstruction Acute ... Hypothyroidism Chronic ... Sclerosis, Spinal Injury
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Algorithm Assess ... >20) - Obtain abdominal ... exclude other causes ... kidney injury with ... HCV, DILI, HCC,
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... and Management ... infectious disease caused ... weeks incubation Acute ... , rectum 80%) (abdominal
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