16 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
transformation to acute ... Allogeneic stem cell ... only curative treatment ... #Management #treatment ... #hematology #oncology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
in those with CLD ... months without treatment ... Drug-Induced Liver Injury ... Failure #Cirrhosis #Hepatology ... #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Diagnosis: • ... microglobulin Treatment ... ’s lymphoma or acute ... #workup #oncology ... #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... Consider stem cell ... progress to MDS or acute ... #management #treatment ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... minimal tumor burden Diagnosis ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Myocarditis 

5 Principles of
Myocarditis:
1. Build clinical suspicion
2. Decide on EMBx
3. Manage acute cardiac injury
4. Manage chronic
Manage acute cardiac ... injury 4. ... Low voltage Treatment ... #Myocarditis #diagnosis ... #management #cardiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... Renal Failure Treatment ... #management #hematology ... #oncology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
) • Use of B-cell ... with severe liver injury ... > 3 mg/dL) or acute ... #Indications #management ... #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... pattern of liver injury ... Hepatitis (eg Viral) Management ... regarding need for treatment ... #Management #Hepatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presents as an acute ... Low or absent NK cell ... • Bicytopenia Treatment ... #management #treatment ... #hematology