13 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... Type of Liver Injury ... #Medications ... #Differential # ... #LiverInjury #Hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... dose dependent injury ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Induced Liver Injury ... involvement, Kidney injury ... duration), Several medications ... DrugInduced #Liver #Injury ... Diagnosis #Algorithm #hepatology
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Indications for ... Albumin for Management ... • Acute kidney injury ... terlipressin #Albumin #Indications ... #treatment #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... Drug-Induced Liver Injury ... (DILI) Viral Hepatitis ... Procedures Management ... Failure #Cirrhosis #Hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential ... Differential Diagnosis ... , HSV, VZV • Medications ... #Differential # ... Diagnosis #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
B - Treatment Indications ... with severe liver injury ... HBV #Treatment #Indications ... #management #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
pattern of liver injury ... Hepatitis (eg Viral) Management ... - Strong indications ... AIH #Diagnosis #Management ... #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
10x ULN), ↑Tbili/Dbili ... infiltration) Differential ... Maternal Support - Critical ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... low-risk disease • Indications ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management