1832 results
Reported Mechanisms and Toxicity of Investigational Treatments for SARS-COV-2
Chloroquine and Hydroxychloroquine
 • Mechanisms: Interference with ligand
Investigational Treatments ... • Mechanisms: Interference ... ligand binding, interference ... into cytosol, decreased ... • Mechanism: Interference
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Elevation == Decreased ... Asplenia Laboratory Interference ... Reduction == Increase ... HgbA1c #Laboratory #Increase ... #Decrease #Diagnosis
COMMONLY ENCOUNTERED MEDICATIONS THAT INCREASE OR DECREASE WARFARIN’S INTERNATIONAL NORMALIZED RATIO (INR)

#Pharmacology #Warfarin #Medications #Interactions #INR
MEDICATIONS THAT INCREASE ... OR DECREASE WARFARIN ... INR #Increases #Decreases
Medications for High-Altitude Sickness 
Acetazolarnide 
 • Carbonic Anydrase Inhibitor Bicarb diuresis & metabolic Acidosis ->
Dexamethasone • Decrease ... vasogenic edema • Decrease ... Nifedipine • Decreases ... Medications #Management #Treatment
Diastolic Dysfunction Grading - Echocardiography
Grade 0  (Normal):
 • E/A >0.8, e’ > 8 cm/s, E/e’
Impaired Relaxation & Decreased ... Compliance • Mild Decrease ... /e’ 8 - 15 • Increase ... Filling • Moderate Decrease ... enlargement • Severe Decrease
COVID-19 - Awake Self-Proning

Physiology of proning:
 - more homogenous ventilation
 - decrease ventral-dorsal transpulmonary pressure difference
ventilation - decrease ... difference - decrease ... compression - increase ... sarscov2 #management #treatment
Noninvasive Positive Pressure Ventilation (NIPPV)

Expiratory & Inspiratory Positive Airway Pressure
Both increase intrathoracic pressure, which can decrease
pressure, which can decrease ... Both can decrease ... larger VT and decreases ... In CHF, decreases ... In COPD, decreases
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
alpha1 > beta 1 • Increase ... • alpha 1 • Increase ... • Inotropy > Increase ... • Inotropy, Decrease ... • Inotropy, Decrease
Assessment of the Child with Chronic Asthma
Are there other allergic disorders?
 - Allergic rhinitis
 - Eczema,
tolerance - Interference ... rhinitis needing treatment
Auto-PEEP 
What is Auto-PEEP?
 • Progressive air trapping & dynamic hyperinflation → ↑Palv at end expiration
barotrauma and decreased ... • Decrease airway ... (Tflow rate = decrease ... I:E ratio, decrease ... RR) • Decrease