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diagnosis causes ild diseases dyspnea hypoxemia hypoxia aids alveolar amiodarone arterial associations chronic comparison connectivetissuediseases ctild gradient hiv induced infections
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm Idiopathic Interstitial Pneumonia • (UIP) Usual Interstitial Pneumonia
Differential Diagnosis ... Interstitial Pneumonia ... Interstitial Pneumonia ... Intersitial Pneumonia ... Interstitial Pneumonia
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
lung diseases ... interstitial pneumonia ... I-JIP: usual interstitial ... AIP: acute interstitial ... PSS: Sjogren syndrome
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
Interstitial Lung ... pneumonia (DIP) ... pneumonia (AIP) ... Churg Strauss syndrome ... ILD #diagnosis #differential
Causes of Hypoxemia- Differential Diagnosis Algorithm Ventilation/perfusion Mismatch • Airway Disease (Asthma, COPD) • Vascular (PE*) •
Diagnosis Algorithm ... Limitation • Interstitial ... lung disease ... Malformation • Severe Pneumonia ... Hypoventilation Syndrome
Approach to the A-a Gradient A-a gradient = PAO2 - PaO2 A-a gradient = [FiO2 x (Patm -
Hypoventilation Syndrome ... Atelectasis, ARDS, Pneumonia ... Lung Disease ... UnremarkableLab #AA ... Hypoxia #hypoxemia #differential
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
in HIV - Differential ... : • 3 syndromes ... fever, rales, interstitial ... Infections #HIV #AIDS #pulmonary ... #differential #
Causes of Dyspnea - Differential Diagnosis Algorithm Cardiac: • Dysrhythmia • Ischemia • Cardiomyopathy • Valvular disease
Diagnosis Algorithm ... Superior vena cava syndrome ... Parenchyma: • Pneumonia ... • Cancer • Interstitial ... lung disease Vasculature
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm Pericardial • Effusion • Cardiac Tamponade* • Constriction Myocardial •
Chronic Dyspnea - Differential ... Diagnosis Algorithm ... Acute Coronary Syndrome ... Alveoli • Pneumonia ... Interstitium
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Amiodarone Induced Lung ... Direct cytotoxic lung ... respiratory distress syndrome ... (e.g., chronic interstitial ... Pleuritic chest
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