9 results
CSF Penetration of Antimicrobials

Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
Penetration of Antimicrobials ... of community-acquired ... other antibiotic classes ... #Antimicrobials ... InfectiousDiseases #Pharmacology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
with appropriate antimicrobial ... therapy • Antimicrobial ... treatment is generally ... required until ... Demyelinating disease caused
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... Immunocompromise Treatment ... Tissue penetration (CNS ... • Secondary to Treatment ... diff) • Hospital-Acquired
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
dysfunction (16%) • Shock ... Thromboembolism (7%) • CNS ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment
Empyema Necessitans (EN) on Chest Wall Physical Examination

Pulmonary teaching case: you are called to the bedside
Pulmonary teaching case ... drain - What’s the diagnosis ... Fusobacterium Treatment ... necessitans includes: - antimicrobials ... surgery is required
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
prophylaxis and treatment ... has a number of CNS ... tinnitus) and may cause ... It also can cause ... Hydroxychloroquine #HCQ #Pharmacology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
& Dry) is the treatment ... essentially Cardiogenic Shock ... the determined cause ... & Dry” is the treatment ... icu #clinical #pharmacology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... Kidney stones caused ... • Hypovolemic shock ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... nervous system (CNS ... • 8%-27% for CNS ... Adenocarcinoma Treatment ... lubricants • Pharmacologic