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management hematology hemophagocytic hlh lymphohistiocytosis 1 cdiff clostridioides clostridium dic difficile disseminated diuresis diuretics excretion gastroenterology hemeonc idsa infection infectiousdiseases
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Perforation) Pathophysiology ... can be community-acquired ... Ileus, Megacolon, Shock ... Treatment Guideline
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... dysfunction (16%) • Shock ... Treat primary cause ... #diagnosis #causes ... #treatment #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Purtilo (XLP) Acquired ... Drugs, Unknown cause ... Treatment: •
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome • Diagnosis ... Kidney stones caused ... • Hypovolemic shock ... Tolvaptan) • Treatment ... #Medications #Table
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... • Secondary (Acquired ... Pathophysiology ... of NK cells and CD8 ... Treatment Approach
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