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hematology differential algorithm management workup aplastic bonemarrow common cvid disorders failure hemeonc hemophagocytic hlh hypogammaglobulinemia immunodeficiency immunology lymphohistiocytosis mcv morphologic
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Marrow Failure Syndromes ... with Pancytopenia ... Acquired Aplastic ... lauraebrown #Pancytopenia ... #diagnosis #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential Diagnosis ... HLH syndrome 5. ... Cytogenetics and FISH • Acquired ... Aplastic Anemia ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential Diagnosis ... HLH syndrome 5 ... Cytogenetics and FISH • Acquired ... Aplastic Anemia ... #Algorithm #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... patients), "Hospital-acquired ... Myelodysplastic syndrome ... #differential #diagnosis ... #causes #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bone marrow + pancytopenia ... and petechiae Causes ... • Peripheral Pancytopenia ... #oncology #hematology ... #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... changes), high MCV anemia ... evaluation: not required ... ITP, unexplained pancytopenia ... #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
growth (e.g.. shock ... • Nephrotic syndrome ... Systemic #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
severe community-acquired ... autoimmune hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
caused by uncontrolled ... • Secondary (Acquired ... Presentation • Common Signs ... - Cytopenias (anemia ... #Management #Hematology
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