13 results
High Output Heart Failure - Pathophysiology and Differential Diagnosis
Obesity - Systemic Vasodilation, Vasoactive Adipokines
Arteriovenous Fistula -
High Output Heart ... Failure - Pathophysiology ... and Differential Diagnosis ... Congenital (e.g., HHT), Acquired ... #cardiology #causes
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... without other cause ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... Purtilo (XLP) Acquired ... Drugs, Unknown cause
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Management Summary Pathophysiology ... epidermis from dermis Clinical ... - Erosions and crusts ... High-potency topical
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... permeability Diagnosis ... Induction Rx: high-dose
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... dysfunction (16%) • Shock ... #Coagulation #diagnosis ... #management #hematology
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Case description ... prior signs or clinical ... common, so maintain high ... #Radiology #diagnosis ... #msk #rheumatology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... with moderate and high ... hypotension or septic shock ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... fractures of feet, thigh ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
extraction is so high ... heart (Sepsis, Shock ... treat the primary cause ... #diagnosis #algorithm ... #management #clinical