18 results
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
(CDI) - Diagnosis ... Perforation) Pathophysiology ... can be community-acquired ... #diagnosis #management ... #treatment #infectiousdiseases
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Auto-amplification loop Diagnosis ... Purtilo (XLP) Acquired ... #management #treatment
Cysticercosis - Taenia solium Life Cycle
1) Eggs or gravid proglottids in feces and passed into environment.
2)
cysticerci. 5) Humans acquire ... intestinal tapeworm infection ... #pathophysiology ... #infectiousdiseases ... #cdc #parasite
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... cells per μL • Diagnosis ... treatment is generally required ... #differential #diagnosis ... opportunistic #InfectiousDiseases
Bacteremia Quick Reference - Treatment Duration

Gram Negative Bacteremia:
 • Avoid: Aminoglycosides and tigecycline
 • Catheters should
removed in septic shock ... follow up cultures required ... of metastatic infection ... Bacteremia #Treatment #Management ... #Duration #infectiousdiseases
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... hypotension or septic shock ... #differential #diagnosis ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Capnocytophaga
Pathogen: Capnocytophaga
 • 9 species, C. canimorsus responsible for the majority of infections
 • Gram-negative rod,
the majority of infections ... malaise • Septic shock ... Cholecystitis Diagnosis ... microbiology #zoonotic #infectiousdiseases ... #diagnosis #management
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
present or signs of infection ... Pathophysiology: ... also important Management ... pyelonephritis CMC ... #management
Trypanosomiasis - Trypanosoma cruzi Life Cycle
1) Triatomine bug takes a blood meal (passes metacyclic trypomastigotes in
amastigotes in new infection ... Tcruzi #LifeCycle #diagnosis ... #pathophysiology ... #infectiousdiseases ... #cdc #parasite
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Complex (MAC): • Acquired ... Advanced HIV (CD4 ... Diagnosis Of NTM ... #differential #diagnosis ... #infectiousdiseases