24 results
management hematology neurology syndrome hemeonc infectiousdiseases aids chronic cll differential hemophagocytic hiv hlh leukemia lymphocytic lymphohistiocytosis rheumatology signs 1 anemia
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Auto-amplification loop Diagnosis ... Purtilo (XLP) Acquired ... Unknown cause Treatment ... #management #treatment
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Clostridioides Difficile Infection ... Toxic Megacolon, Shock ... Perforation) Pathophysiology ... can be community-acquired ... Ileus, Megacolon, Shock
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
acute respiratory symptoms ... Chronic pulmonary symptoms ... Rheumatologic symptoms ... Aspergillosis Pathophysiology ... fever • Septic shock
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... Complications: 1) Infection ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology ... hematology #hemeonc #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... : >3 symptoms, or ... : Infection (sepsis ... management #hematology #oncology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
- Differential Diagnosis ... cells per μL • Diagnosis ... Antimicrobial treatment ... is generally required ... #differential #diagnosis
Thyrotoxic Periodic Paralysis - Illness Script • Epidemiology: Asian men age 20-30 with hyperthyroidism of any
cold exposure, infection ... and menses • Pathophysiology ... thyroid hormone • Symptoms ... or high T3 • Treatment ... Periodic #Paralysis #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... if SSTI or port infection ... abdominal pain; full infectious ... → no immediate treatment ... #HemeOnc #Diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
/Sepsis/Shock, Autoimmune ... Etiology: • Pathophysiology ... Neurological symptoms ... : • Infection, ... epilepticus Treatment
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
to a preceding infection ... than one after symptom ... the underlying pathophysiology ... and cauda equina TREATMENT ... ventilation is required
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