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management hemophagocytic lymphohistiocytosis rheumatology hemeonc syndrome abscess activation cardiology cardiomyopathy causes classification coagulation comparison deficiencies deficiency dermatology differential emergencies encephalopathy
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Purtilo (XLP) Acquired ... HLH: • Infections ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
of Factor IX Acquired ... malnutrition, Antibiotics ... Acute DIC - Septic shock ... #table #comparison ... #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
can mimic common infections ... • Bicytopenia Treatment ... : • Infection ... rapidly, and empiric antibiotic ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
the secondary or acquired ... lymphohistiocytosis (HLH ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
and Management Summary ... polymicrobial infection ... once stable - ... treatment until ... shows a small, stable
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
• Secondary (Acquired ... Triggers: ▪ Infections ... Treatment Approach ... underlying trigger: Infections ... #Management #Hematology
Hepatic Encephalopathy - Diagnosis and Management Summary Definition: • Alteration in brain function manifested by neuropsychiatric symptoms
and Management Summary ... Precipitants: Infection ... non-absorbable antibiotic ... #Management #treatment ... #hepatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... causes such as infectious ... and lower jaw Treatment ... syndrome with acne: antibiotics ... #Dermatology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Cardiomyopathy - Summary ... • Myocardial infarction ... Pts: cardiogenic shock ... during Delivery • Stable ... management #cardiology #treatment
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... if SSTI or port infection ... 500 → may stop antibiotics ... syndrome): - Hematologic ... Oncology #HemeOnc #Diagnosis
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