13 results
Clindamycin - Antibiotics Class Overview
-50 S inhibitor (PO and IV)
Spectrum: Excellent activity vs. Anaerobes and Gram
Clindamycin - Antibiotics ... Class Overview ... including ~ 50% of community-acquired ... skin/soft tissue infections ... , pelvic infections
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
choice, both for treatment ... prophylaxis), Community-acquired ... MRSA Skin infections ... Nocardiosis, Listeria infections ... patients, Salmonella infections
Systemic Inflammatory Response Syndrome (SIRS)
•	Non-specific (infections vs non-infectious)
•	≥2 of the following:
o	Temp >38°C or <36°C
o	HR >90 bpm
o	RR
Non-specific (infections ... vs non-infectious ... host response to infection ... recognition & treatment ... (within 1 hour)
Algorithm for the Evaluation of Acute Diarrhea (< 7 days)
Are the following present?
   1.
hospitalization or antibiotics ... Community water-borne ... HIV infection or ... Consider empiric antibiotic ... Hospitalization required
Tetracyclines – Doxycycline, Tetracycline, Minocycline - Antibiotics Class Overview

- 30S Inhibitors (PO and IV)
Spectrum: Fairly broad
Class Overview ... and soft tissue infections ... when suspect community-acquired ... respiratory tract infections ... , and unusual infections
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Clostridioides Difficile Infection ... Toxic Megacolon, Shock ... nosocomial infection ... post-ABx, but can be community-acquired ... #Clostridium #Infection
Monobactam - Aztreonam - Antibiotics Class Overview

Spectrum: only has activity vs. aerobic gram negatives, no gram
Class Overview ... for: hospital acquired ... intraabdominal infections ... and soft tissue infections ... Main advantages:1)
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
host response to infection ... SEPTIC SHOCK is ... Patients w/ septic shock ... recognition and treatment ... broad spectrum antibiotics
CSF Penetration of Antimicrobials

Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
of community-acquired ... classes. 1 only ... in clinical CNS infections ... susceptible CNS infections ... of CNS infections
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
usually appear in 1- ... • Management: 1. ... progressive inflammatory infection ... including DM • Treatment ... - Antibiotic