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pharmacology diagnosis management overview infectiousdiseases sepsis sirs acute algorithm antimicrobials antipseudomonal antipseudomonas aztreonam bactrim cdi cdiff classification clindamycin clostridioides clostridium
Systemic Inflammatory Response Syndrome (SIRS) • Non-specific (infections vs non-infectious) • ≥2 of the following: o Temp >38°C or <36°C o HR >90 bpm o RR
Non-specific (infections ... vs non-infectious ... host response to infection ... recognition & treatment ... (within 1 hour)
Clindamycin - Antibiotics Class Overview -50 S inhibitor (PO and IV) Spectrum: Excellent activity vs. Anaerobes and Gram
Clindamycin - Antibiotics ... including ~ 50% of community-acquired ... skin/soft tissue infections ... , pelvic infections ... #Review #Overview
Algorithm for the Evaluation of Acute Diarrhea (< 7 days) Are the following present? 1.
hospitalization or antibiotics ... Community water-borne ... HIV infection or ... Consider empiric antibiotic ... Hospitalization required
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Clostridioides Difficile Infection ... Toxic Megacolon, Shock ... nosocomial infection ... post-ABx, but can be community-acquired ... #Clostridium #Infection
Sulfonamides - Antibiotics Class Overview BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic Spectrum: Wide
prophylaxis), Community-acquired ... MRSA Skin infections ... Nocardiosis, Listeria infections ... patients, Salmonella infections ... #Review #Overview
Tetracyclines – Doxycycline, Tetracycline, Minocycline - Antibiotics Class Overview - 30S Inhibitors (PO and IV) Spectrum: Fairly broad
and soft tissue infections ... when suspect community-acquired ... respiratory tract infections ... , and unusual infections ... #Review #Overview
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
Antibiotics are ... treat bacterial infections ... 𝐢𝐧𝐜𝐥𝐮𝐝𝐞𝐬: 1. ... Imagine treatments ... and effective relief
Monobactam - Aztreonam - Antibiotics Class Overview Spectrum: only has activity vs. aerobic gram negatives, no gram
for: hospital acquired ... intraabdominal infections ... and soft tissue infections ... Main advantages:1) ... #Review #Overview
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Disseminated Infections ... 50% in chronic infection ... weeks for acute infection ... clinical forms: 1) ... fever • Septic shock
Sepsis - Diagnosis and Management Life-threatening organ dysfunction caused by a dysregulated host response to infection SEPTIC SHOCK
host response to infection ... SEPTIC SHOCK is ... Patients w/ septic shock ... recognition and treatment ... broad spectrum antibiotics
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