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diagnosis infectiousdiseases hematology pharmacology antibiotics cap idsa indications neurology pulmonary rheumatology activation adjuvant amiodarone bacteremia barre canimorsus capnocytophaga cdc cdc2021
Adjuvant therapies in critical care: steroids to treat infectious diseases - Severe Community Acquired Pneumonia
Acquired Pneumonia ... SCAP severe community-acquired ... respiratory distress syndrome ... #Pharmacology #Management ... #Treatment #Indications
Summary of Infections in which Steroids play a role in treatment • TB meningitis • TB
play a role in treatment ... Severe Pneumocystis pneumonia ... • COVID-19 pneumonia ... Refractory septic shock ... #management #treatment
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Epidemiology: • #1 ... post-ABx, but can be community-acquired ... Ileus, Megacolon, Shock ... 10 mg/kg IV x 1
Antibiotic treatment durations for first line antibiotics recommended by Public Health England (PHE) guidance • Acute
Antibiotic treatment ... acquired pneumonia ... acquired pneumonia ... and CRB65=1 7-10 ... #Antibiotics #management
Antibiotics for severe community-onset pneumonia Atypical coverage always - Usually azithromycin 500 mg daily - Doxycycline
pneumonia Atypical ... piperacillin-tazobactam Septic Shock ... - Linezolid 1 ... #Acquired #Pneumonia ... Antibiotics #Coverage #Management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... and 1:50,000 patients ... frequent and severe community-acquired ... infections: Pneumonia ... : • Nephrotic syndrome
Community Acquired Pneumonia (CAP) - Diagnosis and Management Pneumonia Signs/Symptoms: • Confusion/disorientation (LR + 1.9) • Cough
Community Acquired ... Diagnosis and Management ... Egophony (May appear 1- ... #treatment #Pulmonary ... #Community #Acquired
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
Syndrome (STSS) ... IVIG 1g/kg on day 1, ... day 2 + 3 BIDMC Infectious ... #Syndrome #STSS ... #treatment #management
Systemic Inflammatory Response Syndrome (SIRS) • Non-specific (infections vs non-infectious) • ≥2 of the following: o Temp >38°C or <36°C o HR >90 bpm o RR
Inflammatory Response Syndrome ... Septic Shock • ... >2 mmol/L Management ... recognition & treatment ... (within 1 hour)
Chlamydial Infections - CDC 2021 Treatment Guidelines Recommended Regimen: • Adults and adolescents: doxycycline 100 mg orally
Chlamydial Infections ... - CDC 2021 Treatment ... ophthalmia and pneumonia ... Treatment #Guidelines ... #Management #STI
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