13 results
Lactic Acidosis Classification - Type A vs Type B
Type A Lactic Acidosis: Sepsis, Ischemic bowel, Hemorrhagic
bowel, Hemorrhagic shock ... Hypoperfusion, Cardiogenic shock ... Type B Lactic Acidosis ... Short bowel (D-lactate ... #differential #
Lactic Acidosis - Classification and Differential Diagnosis
Type A Lactic Acidosis: Inadequate Oxygen Delivery
 • Anaerobic muscular
Classification and Differential ... hypoperfusion, Shock ... inborn errors of metabolism ... Classification #Differential ... #TypeB #lactate
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential ... impairment of cellular metabolism ... sweat) - its metabolism ... ->treatments include ... before beginning treatment
Metabolic Acidosis with Anion Gap - KILU Mnemonic

K - Ketoacidosis
	• DKA
		- With normal glucose, ask if
Metabolic Acidosis ... • Type A = tissue ... hypoxia (e.g. shock ... #Acidosis #diagnosis ... #differential
Anion Gap Metabolic Acidosis
 • Diabetic Ketoacidosis ± Hyperglycemia ± Hyperosmolar
 • Alcoholic Ketoacidosis ± Hyperglycemia
Anion Gap Metabolic ... Hyperglycemia • Shock ... Ethylene glycol • Type ... 3rEtbK8 #AnionGap #Metabolic ... #Acidosis #differential
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
- Differential Diagnosis ... Framework Type ... Cardiogenic & Septic Shock ... Inborn Errors of Metabolism ... #Differential #
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
show anion-gap metabolic ... acidosis 4) Presentation ... Pulmonary edema, Shock ... Alkalosis, High Lactate ... diagnosis #management #Treatment
Type B Lactic Acidosis
Elevated lactic acid when no systemic hypoperfusion is apparent
Causes:
 • Drugs (metformin, linezolid,
Type B Lactic Acidosis ... to clear) • D-lactate ... inborn errors of metabolism ... #Lactic #Acidosis ... #causes #differential
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
AQP-2 gene - Acquired ... Obstructive uropathy, Metabolic ... Treatment is aimed ... Classification #Types ... Nephrology #Diagnosis #Differential
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... infusions) - Metabolic ... acidosis - Hyperkalemia ... Hypoaldosteronism • Acquired ... Failure • SLE • Type