14 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Liver Failure (ACLF ... Guidelines ACLF ... months without treatment ... Failure Infections Alcohol-Associated ... Failure #Cirrhosis #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... HSV • Toxic: Alcohol ... Hepatic Artery: Shock ... Medication, Pregnancy, Alcoholic ... Acute #algorithm #hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
of Factor IX Acquired ... Liver Disease - Alcohol ... Acute DIC - Septic shock ... comparison #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... for HIV, HCV - Alcohol ... evaluation: not required ... or if a primary hematologic ... #Workup #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
patients), "Hospital-acquired ... Non-megaloblastic: Alcohol ... independent of alcohol ... differential #diagnosis #causes ... #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... HEV, EBV, CMV), Alcohol-related ... Diagnosis #Algorithm #hepatology
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
neuropsychiatric symptoms • Caused ... rule out other causes ... Constipation, Alcohol ... Initiate empiric treatment ... #hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... exclude other causes ... Multiorgan failure or shock ... prednisolone #Alcoholic ... Management #Algorithm #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
dysfunction (16%) • Shock ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
* Bloating not required ... for diagnosis Treatment ... Rifaximin- up to 3 courses ... Gastroenterology and Hepatology ... gastroenterology #treatment