11 results
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
steroids to treat infectious ... Acquired Pneumonia ... SCAP severe community-acquired ... respiratory distress syndrome ... Pharmacology #Management #Treatment
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Epidemiology: • #1 ... post-ABx, but can be community-acquired ... Ileus, Megacolon, Shock ... 10 mg/kg IV x 1
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... and 1:50,000 patients ... frequent and severe community-acquired ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
Syndrome (STSS) ... necrosis STSS Treatment ... IVIG 1g/kg on day 1, ... day 2 + 3 BIDMC Infectious ... #Syndrome #STSS
IDSA Recommendations for Treating Mucosal Candidiasis in HIV-AIDS
Oropharyngeal Candidiasis: Initial Episodes (Duration of Therapy: 7–14 days)
Preferred
IDSA Recommendations ... 4–6 mL QID or 1– ... antifungals are required ... candida #mucosal #IDSA ... opportunistic #infections
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
appear in 1-2 days ... • Management: 1. ... progressive inflammatory infection ... including DM • Treatment ... diagnosis #management #treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... • Incidence: 1 ... and cauda equina TREATMENT ... ventilation is required ... Guillain #Barre #Syndrome
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Preeclampsia, Eclampsia, Infection ... /Sepsis/Shock, Autoimmune ... PRES Diagnosis: 1. ... Diagnosis: • Infection ... epilepticus Treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... the secondary or acquired ... cytokines, such as IL-1 ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids
CSF Penetration of Antimicrobials

Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
documenting successful treatment ... of community-acquired ... antibiotic classes. 1 ... in clinical CNS infections ... of CNS infections