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diagnosis differential neurology scleroderma vasculitis ana antibodies antinuclear autoantibodies classification cord disorders erythematosus lupus management mimickers ms multiple myopathy patterns
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Systemic Sclerosis ... involve DIP • Myositis ... @AnnKumfer #Systemic ... #diagnosis #signs ... #symptoms #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... autoimmune disease ... and Symptoms: ... acro-osteolysis, myositis ... #SSc #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... weakness, less systemic ... symptoms, and less ... , holster sign, ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... Sjögren Syndrome, Myositis ... Thyroid, Autoimmune ... ANA #patterns #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
anemia 4% - Myositis ... malignancies, Multiple sclerosis ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
(MS) is an autoimmune-mediated ... central nervous system ... neuritis • Partial myelitis ... /SYMPTOMS: • CENTRAL ... Signs and symptoms
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... : - Multiple sclerosis ... , Scleroderma, Systemic ... sclerosis - MCTD ... differential #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Conjunctivitis, mucositis ... Symptoms (Sx) in ... , particularly scleritis ... purpura: strong sign ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Symptoms (SX) in ... , particularly scleritis ... purpura: Strong sign ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... papules and Gottron sign ... ) • Shawl sign ... • Conduction system ... #rheumatology #
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