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diagnosis differential erythematosus lupus sle autoimmune scleroderma sclerosis vasculitis autoantibodies chronic classification cll disorders eosinophil eosinophilia leukemia lymphocytic mimickers myopathy
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Systemic Sclerosis ... involve DIP • Myositis ... @AnnKumfer #Systemic ... Scleroderma #diagnosis #signs ... #symptoms #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
and Symptoms: ... acro-osteolysis, myositis ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... heliotrope rash, Shaw sign ... , holster sign, ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Glomerulonephritis Myositis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... SLE) - Typical Signs ... /Symptoms Alopecia ... Arthralgia / arthritis, Myositis ... #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... anemia 4% - Myositis ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... with no early symptoms ... Physical Exam/Signs ... Leukemia #diagnosis #workup ... #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Conjunctivitis, mucositis ... central nervous system ... Symptoms (Sx) in ... purpura: strong sign ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Symptoms (SX) in ... purpura: Strong sign ... Conjunctivitis, mucositis ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
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