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diagnosis differential lupus treatment sle erythematosus classification druginduced hemophagocytic hlh lymphohistiocytosis oncology summary testing thrombocytopenia vasculitis adult aosd arteritis arthritis
Manifestations of IgG4-related disease by organ system. The most common primary disease features are indicated in
Manifestations of IgG4 ... by organ system ... #IgG4 #Manifestations ... #Hematology #Signs ... #Symptoms
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... female, asian • Systemic ... #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... Evolution: Chronic disease ... #SLE #lupus #Systemic ... #Summary #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... sclerosis, Still's disease ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... PT, aPTT(liver disease ... pylori test (GI symptoms ... Quantitative IgA, IgG ... #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... - ANA > 95% (IgG ... months to years) Systemic ... Evolution: Chronic disease ... comparison #table #rheumatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
failure PBC Signs ... and Symptoms: ... group cholangitis, IgG4 ... cholangitis #diagnosis #workup ... #hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hemolytic anemia) • Systemic ... : • Low serum IgG ... trough levels of IgG ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
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