11 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... dys- (abnormal) -plastic ... #Syndrome #MDS ... #hematology #oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... and symptoms: ... megaloblastic anemia Treatment ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
• Hypocellular myelodysplastic ... syndrome (MDS) ... anemia Treatment ... • Improve the symptoms ... Anemia #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Causes • Anemia • Aplastic ... factor (GCSF) treatments ... treatment (examples ... #hematology #oncology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... WBC >100k, + lab signs ... organ damage • Treatment ... diagnosis #management #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Pure red cell aplasia ... microglobulin Treatment ... • Richter’s Syndrome
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... meningitis), MCC CNS symptoms ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... and symptoms can ... • Bicytopenia Treatment ... #hematology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
Myelodysplastic ... syndromes current ... treatment algorithm ... 24 May 2018 Myelodysplastic ... syndromes (MDS)