540 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute Liver ... Hepatocellular - Liver ... Artery: Shock Liver ... Cholestatic - Intrahepatic ... Cholestatic - Extrahepatic
Causes of Portal Hypertension According to Site of Vascular Obstruction
1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
including surgery 2) Intrahepatic ... Cirrhosis, Polycystic liver ... malignant disease 4) Intrahepatic
Portal Hypertension Classification by site of vascular obstruction
1) Post-hepatic Post-sinusoidal: Budd-Chiari syndrome
2) Intrahepatic Post-sinusoidal: Veno-occlusive disease
3)
Budd-Chiari syndrome 2) Intrahepatic ... Cirrhosis, Polycystic liver ... malignant disease 4) Intrahepatic
Approach to the Hospitalized Patient with Cirrhosis
1) Recognize and Manage Decompensation
 • Ascites
 • Variceal Bleeding
• Transjugular Intrahepatic ... Portosystemic Shunt • Liver
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
transfusion Acute intrahepatic ... progressing to acute liver ... Liver transplant
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... phosphatase (AlkP) - Liver ... nucleotidase - Liver ... Biliary obstruction, intrahepatic ... LouLectures #Liver
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
No dilation = intrahepatic ... MRCP, ERCP, liver
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Causes of Acute Liver ... Injury: • Extrahepatic ... Choledochal cyst • Intrahepatic ... normal, ALP is from extrahepatic
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... malaise) → Acute liver ... Preeclampsia, HELLP, Intrahepatic ... Transfer to a liver
Causes of Intrahepatic Gas
Non-Iatrogenic:
 • Biliary: Emphysematous cholecystitis, Ascending cholangitis, Enteric-biliary fistula, Biliary-bronchopleural fistula, Congenital incompetent
Causes of Intrahepatic ... Hepatic infarction/liver ... transplantation, Trauma, Liver ... changes of the liver ... Embolization #Intrahepatic