11 results
Stages in the Development of Diabetes Type 1

#Diabetes #Type1 #TypeI #DM1 #Stages #Development #Pathophysiology #Timeline #Diagnosis
#Type1 #TypeI #DM1 ... #Development #Pathophysiology ... #Timeline #Diagnosis ... #Endocrinology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... Toxicities: Weight gain ... Sulfonylureas #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... Toxicities: • Joint pains ... DPP4 #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
injection site pain ... GLP1 #Agonists #Pharmacology ... Dosing #Diabetes #DM2 ... #Endocrinology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... - Diagnostic Framework ... necrosis, Charcot (DM2 ... #Joint #Pain #MSK ... #rheumatology #
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... Insulin resist + DM ... malignancy Pathophysiology ... #Management #Endocrinology ... #Treatment #Pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... day vs. 2.5 mg/m2 ... effusions, weight gain ... opacities • Diagnosis ... #management #hematology
Insulin Calculations for Type 1 Diabetes 

Insulin-to-Carb Ratio (ICR) 500/TDD = #g of carbs covered by
utilized in 2 main ... Type1 #Diabetes #DM1 ... #Pharmacology # ... Endocrinology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... pneumonia • DM ... Lung Abscess Pathophysiology ... Pleuritic chest pain ... Lung Abscess Diagnosis
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... Dermatomyositis (PM/DM ... ANA #patterns #rheumatology ... #diagnosis #differential