18 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Dermatomyositis Erythema chronicum ... gangrenosum • IBD • RA ... Sarcoidosis #dermatology ... #differential #diagnosis ... #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
(RA) or systemic ... erythematosus (SLE ... ) Signs / Symptoms ... #Pathophysiology ... #Diagnosis #Signs
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... of hip (rare), Arthritis ... Demyelinating syndromes ... #signs #symptoms ... #diagnosis #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... anti-synthetase syndrome ... myositis, and arthritis ... #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... Recurrent and chronic ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... Symmetrical: • RA ... #MSK #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
juvenile idiopathic arthritis ... juvenile idiopathic arthritis ... erythematosus [SLE ... #Diagnosis #Management ... #Hematology #Rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
, Arthritis, myalgia ... months to years) Systemic ... : Chronic disease ... comparison #table #rheumatology ... #diagnosis #management