7 results
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... have extra nodal involvement ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology ... #differential #algorithm
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
64%) • Renal dysfunction ... Thromboembolism (7%) • CNS involvement ... Schistocytes, helmet cells ... causes #treatment #management ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... for other organ involvement ... of extranodal involvement ... #hematology #oncology ... #management
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... progressive organ dysfunction ... complement • Classification ... IGG4 #Diagnosis #Management ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
genetic immune dysfunction ... multiple organ involvement ... Low or absent NK cell ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
various tissues, leading ... • Endocrine Dysfunction ... marrow: Organ dysfunction ... for endocrine dysfunctions ... Histiocytosis #Diagnosis #Management
Invasive Fungal Infection (IFI)

Invasive fungal infections are severe infections in which fungal pathogens invade normally sterile
with neutropenia, hematologic ... organ or stem cell ... (commonly CNS involvement ... include fever, organ dysfunction ... when feasible Management