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diagnosis liver dili abdominal acute aki bone cardiology chestpain disease distention drug druginduced hematology hepatitis hepatocellular idiosyncratic induced joint kidney
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Chest Pain - Differential Diagnosis Algorithm Cardiovascular Causes: - Outflow Obstruction • Aortic
Chest Pain - Differential ... Diagnosis Algorithm ... Aortic Stenosis - Ischemic ... Embolism (chest pain ... • Muscular Injury
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Diagnosis Algorithm ... Drugs/Toxins • Ischemia ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Causes
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential ... • Vascular: Ischemic ... Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... • Mechanism: ischemic ... • Most common sites ... • Differentiate ... #hematology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Other • ATN: Ischemia ... Diagnosis #nephrology #causes ... #algorithm
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... disease, Hepatic ischaemia ... disorder (e.g. ascites ... #hepatology
Abdominal Distention - Differential Diagnostic Algorithm Ascites Bowel Dilatation Other Causes Mechanical Obstruction • Adhesions 60% • Volvulus 3% •
Diagnostic Algorithm ... Ascites Bowel ... Dilatation Other Causes ... Infectious • Ischemic ... Sclerosis, Spinal Injury
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