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diagnosis differential management oncology antiphospholipid apls breakthrough disorders dvt emergencies eosinophil eosinophilia essential et genitals hemeonc hypercoagulable leukostasis lysis mds
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
Subtherapeutic Anticoagulation ... Structural - Pelvic masses ... - May-Thurner syndrome ... #hematology #differential ... #algorithm
Genital Skin Ulcers - Differential Diagnosis Algorithm Painful: • Herpes simplex • Haemophilus ducreyi (chancroid) • Behcet's
Differential Diagnosis Algorithm ... ) • Behcet's syndrome ... Ulcers #ulcerative #skinrash ... #dermatology #Differential ... #causes
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... 1,500 cells/µL Workup ... glucocorticoid treatment ... Differential #diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... AKI, acute limb ischemia ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... skin that are caused ... Workup: • Complete ... #diagnosis #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... ): - Hematologic ... Treat underlying cause ... stenting - Consider anticoagulation
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... Hypercoagulable Workup ... Algorithm INDICATIONS ... maternal chromosomal causes ... #hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... • Treatment algorithms ... Hydroxyurea + anticoagulation ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
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